human TARS shRNA silencing AAV

Name 
AAV-h-TARS-shRNA
Cat No 
shAAV-224975
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human TARS.

shAAV-224975
AAV-h-TARS-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TARS (threonyl-tRNA synthetase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
threonine tRNA ligase 1, cytoplasmic; threonine--tRNA ligase, cytoplasmic; Threonyl-tRNA synthetase; threonyl-tRNA synthetase, cytoplasmic; ThrRS
Description (eCommerce)
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Threonyl-tRNA synthetase (TARS) belongs to the class-II aminoacyl-tRNA synthetase family [taken from NCBI Entrez Gene (Gene ID: 6897)].
Description (Vector)
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Threonyl-tRNA synthetase belongs to the class-II aminoacyl-tRNA synthetase family
Gene ID
6897
Gene Name (eCommerce)
threonyl-tRNA synthetase
Gene Name (Vector)
threonyl-tRNA synthetase
Gene Symbol
TARS
HGNC ID
HGNC:11572
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2172
ORF Size (bp)
2172 bp
Protein Name (eCommerce)
Threonine--tRNA ligase, cytoplasmic
RefSeq ID
NM_152295
RefSeq Synonyms
NM_152295, NM_001258438, NM_001258437, BC010578, BC000517,
Research Areas
Cytoskeleton,Gene Expression,Translational Control
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Threonyl-tRNA synthetase (TARS) belongs to the class-II aminoacyl-tRNA synthetase family [taken from NCBI Entrez Gene (Gene ID: 6897)].
UniGene ID
Hs.481860
UniProt ID (eCommerce)
P26639

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.