human TAPBPL shRNA silencing AAV

Name
AAV-h-TAPBPL-shRNA

Cat No
shAAV-224969

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human TAPBPL.

shAAV-224969

AAV-h-TAPBPL-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TAPBPL (TAP binding protein like). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

TAPBP-R; TAPBPR

Description (Vector)

Tapasin, or TAPBP (MIM 601962), is a member of the variable-constant Ig superfamily that links major histocompatibility complex (MHC) class I molecules to the transporter associated with antigen processing (TAP; see MIM 170260) in the endoplasmic reticulum (ER). The TAPBP gene is located near the MHC complex on chromosome 6p21.3. TAPBPL is a member of the Ig superfamily that is localized on chromosome 12p13.3, a region somewhat paralogous to the MHC.(supplied by OMIM, Mar 2008)

Gene ID

55080

Gene Name (Vector)

TAP binding protein like

Gene Symbol

TAPBPL

HGNC ID

HGNC:30683

ORF Size (aa)

1407

ORF Size (bp)

1407 bp

RefSeq ID

NM_018009

RefSeq Synonyms

NM_018009, BC015017,

Species

human

UniGene ID

Hs.504597

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.