human TAOK1 shRNA silencing AAV

Name
AAV-h-TAOK1-shRNA

Cat No
shAAV-224958

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human TAOK1.

shAAV-224958

AAV-h-TAOK1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TAOK1 (TAO kinase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

hKFC-B; hTAOK1; KFC-B; kinase from chicken homolog B; MAP3K16; MARK Kinase; MARKK; microtubule affinity regulating kinase kinase; prostate-derived STE20-like kinase 2; prostate-derived sterile 20-like kinase 2; PSK2; PSK-2; serine/threonine protein kinase TAO1 homolog; serine/threonine-protein kinase TAO1; STE20-like kinase PSK2; TAO1; TAOK1; thousand and one amino acid protein 1; thousand and one amino acid protein kinase 1

Description (eCommerce)

TAOK1 is part of the ste20 family of kinases that is able to activate p38 MAP kinase pathway via phosphorylation and activation of upstream MKK3.

Gene ID

57551

Gene Name (eCommerce)

TAO kinase 1

Gene Name (Vector)

TAO kinase 1

Gene Symbol

TAOK1

HGNC ID

HGNC:29259

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

3006

ORF Size (bp)

3006 bp

Protein Name (eCommerce)

Serine/threonine-protein kinase TAO1

RefSeq ID

NM_020791

RefSeq Synonyms

NM_025142, NM_020791, BC144067, BC133039,

Research Areas

Apoptosis,Cell Cycle,Cytoskeleton,DNA Damage/Repair,JNK Signaling,Kinase/Phosphatase,MAPK Signaling,Signal Transduction

Research Areas (Faceted)

signal_transduction,cell_biology,cell_cycle,genetics,transcription_translation,signal_transduction,cell_biology

Species

human

Target Sentence

TAOK1 is part of the ste20 family of kinases that is able to activate p38 MAP kinase pathway via phosphorylation and activation of upstream MKK3.

UniGene ID

Hs.631758

UniProt ID (eCommerce)

Q7L7X3

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.