human TALDO1 shRNA silencing AAV

Name
AAV-h-TALDO1-shRNA

Cat No
shAAV-224953

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human TALDO1.

shAAV-224953

AAV-h-TALDO1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TALDO1 (transaldolase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

dihydroxyacetone transferase; glycerone transferase; TAL; TALDOR; TALH; TAL-H; testicular secretory protein Li 56; transaldolase

Description (eCommerce)

Transaldolase is important for the balance of metabolites in the pentose-phosphate pathwayÂ [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P37837].

Description (Vector)

Transaldolase 1 is a key enzyme of the nonoxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This pathway can also maintain glutathione at a reduced state and thus protect sulfhydryl groups and cellular integrity from oxygen radicals. The functional gene of transaldolase 1 is located on chromosome 11 and a pseudogene is identified on chromosome 1 but there are conflicting map locations. The second and third exon of this gene were developed by insertion of a retrotransposable element. This gene is thought to be involved in multiple sclerosis.

Gene ID

6888

Gene Name (eCommerce)

transaldolase 1

Gene Name (Vector)

transaldolase 1

Gene Symbol

TALDO1

HGNC ID

HGNC:11559

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

1014

Protein Name (eCommerce)

Transaldolase

RefSeq ID

NM_006755

RefSeq Synonyms

NM_006755, BC010103, BC009680,

Research Areas

Metabolism/Metabolic Process

Research Areas (Faceted)

cell_biology,metabolism

Species

human

Target Sentence

Transaldolase is important for the balance of metabolites in the pentose-phosphate pathwayÂ [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P37837].

UniGene ID

Hs.438678

UniProt ID (eCommerce)

P37837

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.