human TAGLN shRNA silencing AAV

Name
AAV-h-TAGLN-shRNA

Cat No
shAAV-224943

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human TAGLN.

shAAV-224943

AAV-h-TAGLN-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TAGLN (transgelin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

SM22; SMCC; TAGLN1; WS3-10

Description (Vector)

TAGLN is a transformation and shape-change sensitive actin cross-linking/gelling protein found in fibroblasts and smooth muscle. Its expression is down-regulated in many cell lines, and this down-regulation may be an early and sensitive marker for the onset of transformation. A functional role of this protein is unclear. Two transcript variants encoding the same protein have been found for this gene.

Gene ID

6876

Gene Name (Vector)

transgelin

Gene Symbol

TAGLN

HGNC ID

HGNC:11553

ORF Size (aa)

606

RefSeq ID

NM_003186

RefSeq Synonyms

NM_003186, NM_001001522, BC093050, BC092415, BC065829, BC004927,

Species

human

UniGene ID

Hs.410977

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.