human SYT1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human SYT1.
shAAV-224836
AAV-h-SYT1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human SYT1 (synaptotagmin 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
P65; SVP65; SYT
Description (Vector)
The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin-1 participates in triggering neurotransmitter release at the synapse (Fernandez-Chacon et al., 2001 (PubMed 11242035)).(supplied by OMIM, Jul 2010)
Gene ID
6857
Gene Name (Vector)
synaptotagmin 1
Gene Symbol
SYT1
HGNC ID
HGNC:11509
ORF Size (aa)
1269
ORF Size (bp)
1269 bp
RefSeq ID
NM_005639
RefSeq Synonyms
NM_005639, NM_001291901, NM_001135806, NM_001135805, BC058917,
Species
human
UniGene ID
Hs.310545
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.