human SUOX shRNA silencing AAV

Name
AAV-h-SUOX-shRNA

Cat No
shAAV-224748

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human SUOX.

shAAV-224748

AAV-h-SUOX-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SUOX (sulfite oxidase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

Sulfite oxidase is a homodimeric protein localized to the intermembrane space of mitochondria. Each subunit contains a heme domain and a molybdopterin-binding domain. The enzyme catalyzes the oxidation of sulfite to sulfate, the final reaction in the oxidative degradation of the sulfur amino acids cysteine and methionine. Sulfite oxidase deficiency results in neurological abnormalities which are often fatal at an early age. Alternative splicing results in multiple transcript variants encoding identical proteins.

Gene ID

6821

Gene Name (Vector)

sulfite oxidase

Gene Symbol

SUOX

HGNC ID

HGNC:11460

ORF Size (aa)

1638

ORF Size (bp)

1638 bp

RefSeq ID

NM_000456

RefSeq Synonyms

NM_001032387, NM_001032386, NM_000456, BC065193,

Species

human

UniGene ID

Hs.558403

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.