human STAMBP shRNA silencing AAV

Name
AAV-h-STAMBP-shRNA

Cat No
shAAV-224506

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human STAMBP.

shAAV-224506

AAV-h-STAMBP-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human STAMBP (STAM binding protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

AMSH; MICCAP

Description (Vector)

Cytokine-mediated signal transduction in the JAK-STAT cascade requires the involvement of adaptor molecules. One such signal-transducing adaptor molecule contains an SH3 domain that is required for induction of MYC and cell growth. The protein encoded by this gene binds to the SH3 domain of the signal-transducing adaptor molecule, and plays a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.

Gene ID

10617

Gene Name (Vector)

STAM binding protein

Gene Symbol

STAMBP

HGNC ID

HGNC:16950

ORF Size (aa)

1275

ORF Size (bp)

1275 bp

RefSeq ID

NM_006463

RefSeq Synonyms

NM_213622, NM_201647, NM_006463, BC101469, BC101467, BC065574, BC007682,

Species

human

UniGene ID

Hs.657598

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.