human ST6GAL1 shRNA silencing AAV

Name
AAV-h-ST6GAL1-shRNA

Cat No
shAAV-224464

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human ST6GAL1.

shAAV-224464

AAV-h-ST6GAL1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ST6GAL1 (ST6 beta-galactoside alpha-2,6-sialyltransferase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

SIAT1; ST6GalI; ST6N

Description (Vector)

ST6GAL1 encodes a member of glycosyltransferase family 29. The encoded protein is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The protein, which is normally found in the Golgi but can be proteolytically processed to a soluble form, is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CD75, and CD76. ST6GAL1 has been incorrectly referred to as CD75. Three transcript variants encoding two different isoforms have been described.

Gene ID

6480

Gene Name (Vector)

ST6 beta-galactoside alpha-2,6-sialyltransferase 1

Gene Symbol

ST6GAL1

HGNC ID

HGNC:10860

ORF Size (aa)

1221

ORF Size (bp)

1221 bp

RefSeq ID

NM_003032

RefSeq Synonyms

NM_173217, NM_173216, NM_003032, BC040009, BC031476,

Species

human

UniGene ID

Hs.207459

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.