human ST6GAL1 shRNA silencing AAV

Cat. No: shAAV-224464

Availability: 6-8 weeks

Name: AAV-h-ST6GAL1-shRNA

This is an AAV expressing shRNA for silencing of Human ST6GAL1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: ST6GAL1
Gene Name: ST6 beta-galactoside alpha-2,6-sialyltransferase 1
Gene ID: 6480
Gene Synonyms: SIAT1; ST6GalI; ST6N
ORF Size: 1221 bp
RefSeq#: NM_003032
Gene Description: ST6GAL1 encodes a member of glycosyltransferase family 29. The encoded protein is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The protein, which is normally found in the Golgi but can be proteolytically processed to a soluble form, is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CD75, and CD76. ST6GAL1 has been incorrectly referred to as CD75. Three transcript variants encoding two different isoforms have been described.
UniGene ID: Hs.207459
HGNC ID: HGNC:10860