human SPIB shRNA silencing AAV

Name
AAV-h-SPIB-shRNA

Cat No
shAAV-224173

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human SPIB.

shAAV-224173

AAV-h-SPIB-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SPIB (Spi-B transcription factor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

SPI-B

Description (Vector)

SPIB is a transcriptional activator that binds to the PU-box (5'-GAGGAA-3') and acts as a lymphoid-specific enhancer. Four transcript variants encoding different isoforms have been found for this gene.

Gene ID

6689

Gene Name (Vector)

Spi-B transcription factor

Gene Symbol

SPIB

HGNC ID

HGNC:11242

ORF Size (aa)

789

RefSeq ID

NM_003121

RefSeq Synonyms

NM_003121, NM_001244000, NM_001243999, NM_001243998, BC007921,

Species

human

UniGene ID

Hs.437905

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.