human SNX17 shRNA silencing AAV

Name 
AAV-h-SNX17-shRNA
Cat No 
shAAV-223926
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human SNX17.

shAAV-223926
AAV-h-SNX17-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SNX17 (sorting nexin 17). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Description (Vector)
SNX17 encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members, but contains a B41 domain. This protein interacts with the cytoplasmic domain of P-selectin, and may function in the intracellular trafficking of P-selectin. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene ID
9784
Gene Name (Vector)
sorting nexin 17
Gene Symbol
SNX17
HGNC ID
HGNC:14979
ORF Size (aa)
1413
ORF Size (bp)
1413 bp
RefSeq ID
NM_014748
RefSeq Synonyms
NM_014748, NM_001267061, NM_001267060, NM_001267059, BC050590, BC014620, BC002610, BC002524,
Species
human
UniGene ID
Hs.278569

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.