human SNAP29 shRNA silencing AAV

Name
AAV-h-SNAP29-shRNA

Cat No
shAAV-223810

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human SNAP29.

shAAV-223810

AAV-h-SNAP29-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SNAP29 (synaptosome associated protein 29). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CEDNIK; SNAP-29

Description (Vector)

This gene, a member of the SNAP25 gene family, encodes a protein involved in multiple membrane trafficking steps. Two other members of this gene family, SNAP23 and SNAP25, encode proteins that bind a syntaxin protein and mediate synaptic vesicle membrane docking and fusion to the plasma membrane. The protein encoded by this gene binds tightly to multiple syntaxins and is localized to intracellular membrane structures rather than to the plasma membrane. While the protein is mostly membrane-bound, a significant fraction of it is found free in the cytoplasm. Use of multiple polyadenylation sites has been noted for this gene.

Gene ID

9342

Gene Name (Vector)

synaptosome associated protein 29

Gene Symbol

SNAP29

HGNC ID

HGNC:11133

ORF Size (aa)

777

RefSeq ID

NM_004782

RefSeq Synonyms

NM_004782, BC009715,

Species

human

UniGene ID

Hs.108002

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.