human SMARCD3 shRNA silencing AAV

Name
AAV-h-SMARCD3-shRNA

Cat No
shAAV-223727

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human SMARCD3.

shAAV-223727

AAV-h-SMARCD3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SMARCD3 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

BAF60C; CRACD3; Rsc6p

Description (Vector)

SMARCD3 is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and has sequence similarity to the yeast Swp73 protein. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.

Gene ID

6604

Gene Name (Vector)

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3

Gene Symbol

SMARCD3

HGNC ID

HGNC:11108

ORF Size (aa)

1413

ORF Size (bp)

1413 bp

RefSeq ID

NM_003078

RefSeq Synonyms

NM_003078, NM_001003802, NM_001003801, BC110350, BC002628,

Species

human

UniGene ID

Hs.647067

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.