human SLC25A25 shRNA silencing AAV

Name
AAV-h-SLC25A25-shRNA

Cat No
shAAV-223245

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human SLC25A25.

shAAV-223245

AAV-h-SLC25A25-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SLC25A25 (solute carrier family 25 member 25). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

MCSC; PCSCL; SCAMC-2

Description (Vector)

SLC25A25 belongs to the family of calcium-binding mitochondrial carriers, with a characteristic mitochondrial carrier domain at the C-terminus. These proteins are found in the inner membranes of mitochondria, and function as transport proteins. They shuttle metabolites, nucleotides and cofactors through the mitochondrial membrane and thereby connect and/or regulate cytoplasm and matrix functions. This protein may function as an ATP-Mg/Pi carrier that mediates the transport of Mg-ATP in exchange for phosphate, and likely responsible for the net uptake or efflux of adenine nucleotides into or from the mitochondria. Alternatively spliced transcript variants encoding different isoforms with a common C-terminus but variable N-termini have been described for this gene.

Gene ID

114789

Gene Name (Vector)

solute carrier family 25 member 25

Gene Symbol

SLC25A25

HGNC ID

HGNC:20663

ORF Size (aa)

1410

ORF Size (bp)

1410 bp

RefSeq ID

NM_052901

RefSeq Synonyms

NM_052901, NM_001330988, NM_001265614, NM_001006643, NM_001006642, NM_001006641, BC103933, BC103932, BC103931, BC103930, BC089448,

Species

human

UniGene ID

Hs.5476

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.