human SLC22A12 shRNA silencing AAV

Name 
AAV-h-SLC22A12-shRNA
Cat No 
shAAV-223178
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human SLC22A12.

shAAV-223178
AAV-h-SLC22A12-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SLC22A12 (solute carrier family 22 member 12). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
OAT4L; RST; URAT1
Description (Vector)
SLC22A12 is a member of the organic anion transporter (OAT) family and acts as a urate transporter to regulate urate levels in blood. An elevated level of serum urate, hyperuricemia, is associated with increased incidences of gout and mutations in this gene cause renal hypouricemia. This protein is an integral membrane protein primarily found in epithelial cells of the proximal tubule of the kidney.
Gene ID
116085
Gene Name (Vector)
solute carrier family 22 member 12
Gene Symbol
SLC22A12
HGNC ID
HGNC:17989
ORF Size (aa)
1662
ORF Size (bp)
1662 bp
RefSeq ID
NM_144585
RefSeq Synonyms
NM_153378, NM_144585, NM_001276327, NM_001276326, BC053348,
Species
human
UniGene ID
Hs.174424

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.