human SLC22A1 shRNA silencing AAV

Name
AAV-h-SLC22A1-shRNA

Cat No
shAAV-223175

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human SLC22A1.

shAAV-223175

AAV-h-SLC22A1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SLC22A1 (solute carrier family 22 member 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

HOCT1; OCT1; oct1_cds

Description (Vector)

Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. Two transcript variants encoding two different isoforms have been found for this gene, but only the longer variant encodes a functional transporter.

Gene ID

6580

Gene Name (Vector)

solute carrier family 22 member 1

Gene Symbol

SLC22A1

HGNC ID

HGNC:10963

ORF Size (aa)

1665

ORF Size (bp)

1665 bp

RefSeq ID

NM_003057

RefSeq Synonyms

NM_153187, NM_003057, BC126364,

Species

human

UniGene ID

Hs.117367

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.