human SLC1A1 shRNA silencing AAV

Cat. No: shAAV-223163

Availability: 4-5 weeks

Name: AAV-h-SLC1A1-shRNA

This is an AAV expressing shRNA for silencing of Human SLC1A1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SLC1A1
Gene Name: solute carrier family 1 member 1
Gene ID: 6505
Gene Synonyms: DCBXA; EAAC1; EAAT3; SCZD18
ORF Size: 1575 bp
RefSeq#: NM_004170
Gene Description: SLC1A1 encodes a member of the high-affinity glutamate transporters that play an essential role in transporting glutamate across plasma membranes. In brain, these transporters are crucial in terminating the postsynaptic action of the neurotransmitter glutamate, and in maintaining extracellular glutamate concentrations below neurotoxic levels. This transporter also transports aspartate, and mutations in this gene are thought to cause dicarboxylicamino aciduria, also known as glutamate-aspartate transport defect.
UniGene ID: Hs.444915
HGNC ID: HGNC:10939