human SLC18A1 shRNA silencing AAV

Name
AAV-h-SLC18A1-shRNA

Cat No
shAAV-223156

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human SLC18A1.

shAAV-223156

AAV-h-SLC18A1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SLC18A1 (solute carrier family 18 member A1). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CGAT; VAT1; VMAT1

Description (Vector)

The vesicular monoamine transporter acts to accumulate cytosolic monoamines into vesicles, using the proton gradient maintained across the vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine (Peter et al., 1993 (PubMed 7905859)). See also SLC18A2 (MIM 193001).(supplied by OMIM, Mar 2008)

Gene ID

6570

Gene Name (Vector)

solute carrier family 18 member A1

Gene Symbol

SLC18A1

HGNC ID

HGNC:10934

ORF Size (aa)

1158

RefSeq ID

NM_003053

RefSeq Synonyms

NM_003053, NM_001142325, NM_001142324, NM_001135691, BC009387, BC006317,

Species

human

UniGene ID

Hs.158322

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.