human SLC16A3 shRNA silencing AAV

Name 
AAV-h-SLC16A3-shRNA
Cat No 
shAAV-223130
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human SLC16A3.

shAAV-223130
AAV-h-SLC16A3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SLC16A3 (solute carrier family 16 member 3). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
MCT 3; MCT 4; MCT3; MCT-3; MCT4; MCT-4; monocarboxylate transporter 3; monocarboxylate transporter 4; solute carrier family 16 (monocarboxylate transporter), member 3; solute carrier family 16 (monocarboxylic acid transporters), member 3; Solute carrier family 16 member 3; solute carrier family 16, member 3 (monocarboxylic acid transporter 4)
Description (eCommerce)
Monocarboxylate transporter 4 (MCT4) is a proton-linked monocarboxylate transporter. It catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate (By similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O15427].
Description (Vector)
Lactic acid and pyruvate transport across plasma membranes is catalyzed by members of the proton-linked monocarboxylate transporter (MCT) family, which has been designated solute carrier family-16. Each MCT appears to have slightly different substrate and inhibitor specificities and transport kinetics, which are related to the metabolic requirements of the tissues in which it is found. The MCTs, which include MCT1 (SLC16A1; MIM 600682) and MCT2 (SLC16A7; MIM 603654), are characterized by 12 predicted transmembrane domains (Price et al., 1998 (PubMed 9425115)).(supplied by OMIM, Mar 2008)
Gene ID
9123
Gene Name (eCommerce)
solute carrier family 16 member 3
Gene Name (Vector)
solute carrier family 16 member 3
Gene Symbol
SLC16A3
HGNC ID
HGNC:10924
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1398
ORF Size (bp)
1398 bp
Protein Name (eCommerce)
Monocarboxylate transporter 4
RefSeq ID
NM_004207
RefSeq Synonyms
NM_004207, NM_001206952, NM_001206951, NM_001206950, NM_001042423, NM_001042422, BC112269, BC112267,
Research Areas
Cardiovascular,Cytoskeleton,Immunology,Metabolism/Metabolic Process,Transport
Research Areas (Faceted)
cardiovascular,cell_biology,immunology,metabolism,cell_biology
Species
human
Target Sentence
Monocarboxylate transporter 4 (MCT4) is a proton-linked monocarboxylate transporter. It catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate (By similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O15427].
UniGene ID
Hs.500761
UniProt ID (eCommerce)
O15427

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.