human SLC16A1 shRNA silencing AAV

Name 
AAV-h-SLC16A1-shRNA
Cat No 
shAAV-223119
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human SLC16A1.

shAAV-223119
AAV-h-SLC16A1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SLC16A1 (solute carrier family 16 member 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HHF7; MCT; MCT 1; MCT1; MCT1D; monocarboxylate transporter 1; solute carrier family 16 (monocarboxylate transporter), member 1; solute carrier family 16 (monocarboxylic acid transporters), member 1; Solute carrier family 16 member 1; solute carrier family 16, member 1 (monocarboxylic acid transporter 1)
Description (eCommerce)
Monocarboxylate transporter 1 (MCT1) is a proton-linked monocarboxylate transporter. It catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P53985].
Description (Vector)
SLC16A1 is a proton-linked monocarboxylate transporter that catalyzes the movement of many monocarboxylates, such as lactate and pyruvate, across the plasma membrane. Mutations in this gene are associated with erythrocyte lactate transporter defect. Alternatively spliced transcript variants have been found for this gene.
Gene ID
6566
Gene Name (eCommerce)
solute carrier family 16 member 1
Gene Name (Vector)
solute carrier family 16 member 1
Gene Symbol
SLC16A1
HGNC ID
HGNC:10922
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1293
ORF Size (bp)
1293 bp
Protein Name (eCommerce)
Monocarboxylate transporter 1
RefSeq ID
NM_003051
RefSeq Synonyms
NM_003051, NM_001166496, BC045664, BC026317,
Research Areas
Cardiovascular,Immunology,Metabolism/Metabolic Process,Mitochondrion,Transport
Research Areas (Faceted)
cardiovascular,immunology,metabolism,cell_biology
Species
human
Target Sentence
Monocarboxylate transporter 1 (MCT1) is a proton-linked monocarboxylate transporter. It catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P53985].
UniGene ID
Hs.75231
UniProt ID (eCommerce)
P53985

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.