human SKI shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human SKI.
shAAV-223043
AAV-h-SKI-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human SKI (SKI proto-oncogene). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
proto-oncogene c-Ski; SGS; ski oncogene; ski oncoprotein; SKV; v-ski avian sarcoma viral oncogene homolog
Description (eCommerce)
c-Ski is the nuclear proto-oncogene protein homolog of avian sarcoma viral (v-ski) oncogene. It functions as a repressor of TGF-beta signaling, and may play a role in neural tube development and muscle differentiation.
Description (Vector)
SKI encodes the nuclear protooncogene protein homolog of avian sarcoma viral (v-ski) oncogene. It functions as a repressor of TGF-beta signaling, and may play a role in neural tube development and muscle differentiation.
Gene ID
6497
Gene Name (eCommerce)
SKI proto-oncogene
Gene Name (Vector)
SKI proto-oncogene
Gene Symbol
SKI
HGNC ID
HGNC:10896
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2184
ORF Size (bp)
2184 bp
Protein Name (eCommerce)
Ski oncogene
RefSeq ID
NM_003036
RefSeq Synonyms
NM_003036, BC157082, BC156044,
Research Areas
Apoptosis,Cancer,Chromatin Remodeling,Gene Expression,Neurobiology,Neurodevelopment,Notch Signaling,Signal Transduction,TGF-beta Signaling,Transcription Factor/Regulator,Tumor Suppressors/Oncoproteins,Ubiquitination,Wnt Signaling
Research Areas (Faceted)
cancer,signal_transduction,cell_biology,genetics,transcription_translation,neurobiology,developmental_biology,developmental_biology,signal_transduction,immunology,genetics,transcription_translation,cancer,genetics,signal_transduction,developmental_biology
Species
human
Target Sentence
c-Ski is the nuclear proto-oncogene protein homolog of avian sarcoma viral (v-ski) oncogene. It functions as a repressor of TGF-beta signaling, and may play a role in neural tube development and muscle differentiation.
UniGene ID
Hs.663133
UniProt ID (eCommerce)
P12755
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.