human SKAP1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human SKAP1.
shAAV-223041
AAV-h-SKAP1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human SKAP1 (src kinase associated phosphoprotein 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
HEL-S-81p; SCAP1; SKAP55
Description (Vector)
SKAP1 encodes a T cell adaptor protein, a class of intracellular molecules with modular domains capable of recruiting additional proteins but that exhibit no intrinsic enzymatic activity. The encoded protein contains a unique N-terminal region followed by a PH domain and C-terminal SH3 domain. Along with the adhesion and degranulation-promoting adaptor protein, the encoded protein plays a critical role in inside-out signaling by coupling T-cell antigen receptor stimulation to the activation of integrins.
Gene ID
8631
Gene Name (Vector)
src kinase associated phosphoprotein 1
Gene Symbol
SKAP1
HGNC ID
HGNC:15605
ORF Size (aa)
1077
RefSeq ID
NM_003726
RefSeq Synonyms
NM_003726, NM_001075099, BC047870,
Species
human
UniGene ID
Hs.316931
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.