human SH3GLB1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human SH3GLB1.
shAAV-222907
AAV-h-SH3GLB1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human SH3GLB1 (SH3 domain containing GRB2 like endophilin B1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Bif-1; CGI-61; dJ612B15.2; PPP1R70
Description (Vector)
SH3GLB1 encodes a SRC homology 3 domain-containing protein. The encoded protein interacts with the proapoptotic member of the Bcl-2 family, Bcl-2-associated X protein (Bax) and may be involved in regulating apoptotic signaling pathways. This protein may also be involved in maintaining mitochondrial morphology. Alternate splicing results in multiple transcript variants.
Gene ID
51100
Gene Name (Vector)
SH3 domain containing GRB2 like endophilin B1
Gene Symbol
SH3GLB1
HGNC ID
HGNC:10833
ORF Size (aa)
1098
ORF Size (bp)
1098 bp
RefSeq ID
NM_016009
RefSeq Synonyms
NM_016009, NM_001206653, NM_001206652, NM_001206651, BC007455,
Species
human
UniGene ID
Hs.136309
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.