human SGK1 shRNA silencing AAV

Cat. No: shAAV-222850

Availability: 4-5 weeks

Name: AAV-h-SGK1-shRNA

This is an AAV expressing shRNA for silencing of Human SGK1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SGK1
Gene Name: serum/glucocorticoid regulated kinase 1
Gene ID: 6446
Gene Synonyms: SGK
ORF Size: 1296 bp
RefSeq#: NM_005627
Gene Description: SGK1 encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
UniGene ID: Hs.510078
HGNC ID: HGNC:10810