human SFRS2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human SRSF2.
shAAV-222800
AAV-h-SFRS2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human SRSF2 (serine and arginine rich splicing factor 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
PR264; SC-35; SC35; SFRS2; SFRS2A; SRp30b
Description (Vector)
SRSF2 is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants encoding the same protein and one non-coding transcript variant have been found for this gene. In addition, a pseudogene of this gene has been found on chromosome 11.
Gene ID
6427
Gene Name (Vector)
serine and arginine rich splicing factor 2
Gene Symbol
SRSF2
HGNC ID
HGNC:10783
ORF Size (aa)
666
RefSeq ID
NM_003016
RefSeq Synonyms
NM_003016, NM_001195427, BC070086, BC066958, BC001303, BC000339,
Species
human
UniGene ID
Hs.713672
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.