human SEMG1 shRNA silencing AAV

Name
AAV-h-SEMG1-shRNA

Cat No
shAAV-222570

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human SEMG1.

shAAV-222570

AAV-h-SEMG1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SEMG1 (semenogelin I). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CT103; dJ172H20.2; SEMG; SGI

Description (Vector)

SEMG1 is the predominant protein in semen. The encoded secreted protein is involved in the formation of a gel matrix that encases ejaculated spermatozoa. The prostate-specific antigen (PSA) protease processes this protein into smaller peptides, with each possibly having a separate function. The proteolysis process breaks down the gel matrix and allows the spermatozoa to move more freely.

Gene ID

6406

Gene Name (Vector)

semenogelin I

Gene Symbol

SEMG1

HGNC ID

HGNC:10742

ORF Size (aa)

1209

ORF Size (bp)

1209 bp

RefSeq ID

NM_003007

RefSeq Synonyms

NM_003007, BC055416, BC007096,

Species

human

UniGene ID

Hs.1968

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.