human SEMA4G shRNA silencing AAV

Name
AAV-h-SEMA4G-shRNA

Cat No
shAAV-222559

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human SEMA4G.

shAAV-222559

AAV-h-SEMA4G-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SEMA4G (semaphorin 4G). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

Semaphorins are a large family of conserved secreted and membrane associated proteins which possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Based on sequence and structural similarities, semaphorins are put into eight classes: invertebrates contain classes 1 and 2, viruses have class V, and vertebrates contain classes 3-7. Semaphorins serve as axon guidance ligands via multimeric receptor complexes, some (if not all) containing plexin proteins. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene ID

57715

Gene Name (Vector)

semaphorin 4G

Gene Symbol

SEMA4G

HGNC ID

HGNC:10735

ORF Size (aa)

2109

ORF Size (bp)

2109 bp

RefSeq ID

NM_017893

RefSeq Synonyms

NM_017893, NM_001203244, BC128579, BC110382, BC051030, BC020960,

Species

human

UniGene ID

Hs.591923

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.