human SEMA3E shRNA silencing AAV

Cat. No: shAAV-222542

Availability: 6-8 weeks

Name: AAV-h-SEMA3E-shRNA

This is an AAV expressing shRNA for silencing of Human SEMA3E.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SEMA3E
Gene Name: semaphorin 3E
Gene ID: 9723
Gene Synonyms: coll-5; M-SEMAH; M-SemaK; SEMAH
ORF Size: 2328 bp
RefSeq#: NM_001178129
Gene Description: Semaphorins are a large family of conserved secreted and membrane associated proteins which possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Based on sequence and structural similarities, semaphorins are put into eight classes: invertebrates contain classes 1 and 2, viruses have class V, and vertebrates contain classes 3-7. Semaphorins serve as axon guidance ligands via multimeric receptor complexes, some (if not all) containing plexin proteins. This gene encodes a class 4 semaphorin. This gene encodes a class 3 semaphorin. Multiple transcript variants encoding different isoforms have been found for this gene.
UniGene ID: Hs.528721
HGNC ID: HGNC:10727