human SEMA3B shRNA silencing AAV

Name
AAV-h-SEMA3B-shRNA

Cat No
shAAV-222538

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human SEMA3B.

shAAV-222538

AAV-h-SEMA3B-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SEMA3B (semaphorin 3B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

LUCA-1; SemA; SEMA5; SEMAA; semaV

Description (Vector)

The semaphorin/collapsin family of molecules plays a critical role in the guidance of growth cones during neuronal development. The secreted protein encoded by this gene family member is important in axonal guidance and has been shown to act as a tumor suppressor by inducing apoptosis.

Gene ID

7869

Gene Name (Vector)

semaphorin 3B

Gene Symbol

SEMA3B

HGNC ID

HGNC:10724

ORF Size (aa)

1908

ORF Size (bp)

1908 bp

RefSeq ID

NM_004636

RefSeq Synonyms

NM_004636, NM_001290063, NM_001290062, NM_001290061, NM_001290060, NM_001005914, BC024220, BC013975, BC009113,

Species

human

UniGene ID

Hs.82222

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.