human SDHA shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human SDHA.
shAAV-222436
AAV-h-SDHA-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human SDHA (succinate dehydrogenase complex flavoprotein subunit A). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CMD1GG; FP; PGL5; SDH1; SDH2; SDHF
Description (Vector)
SDHA encodes a major catalytic subunit of succinate-ubiquinone oxidoreductase, a complex of the mitochondrial respiratory chain. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. Mutations in this gene have been associated with a form of mitochondrial respiratory chain deficiency known as Leigh Syndrome. A pseudogene has been identified on chromosome 3q29.
Gene ID
6389
Gene Name (Vector)
succinate dehydrogenase complex flavoprotein subunit A
Gene Symbol
SDHA
HGNC ID
HGNC:10680
ORF Size (aa)
1995
ORF Size (bp)
1995 bp
RefSeq ID
NM_004168
RefSeq Synonyms
NM_004168, NM_001330758, NM_001294332, BC041016, BC001380,
Species
human
UniGene ID
Hs.440475
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.