human SCN4B shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human SCN4B.
shAAV-222373
AAV-h-SCN4B-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human SCN4B (sodium voltage-gated channel beta subunit 4). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ATFB17; LQT10; Navbeta4
Description (Vector)
SCN4B is one of several sodium channel beta subunits. These subunits interact with voltage-gated alpha subunits to change sodium channel kinetics. The encoded transmembrane protein forms interchain disulfide bonds with SCN2A. Defects in this gene are a cause of long QT syndrome type 10 (LQT10). Three protein-coding and one non-coding transcript variant have been found for this gene.
Gene ID
6330
Gene Name (Vector)
sodium voltage-gated channel beta subunit 4
Gene Symbol
SCN4B
HGNC ID
HGNC:10592
ORF Size (aa)
357
RefSeq ID
NM_174934
RefSeq Synonyms
NM_174934, NM_001142349, NM_001142348, BC035017,
Species
human
UniGene ID
Hs.65239
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.