human S100A9 shRNA silencing AAV

Name 
AAV-h-S100A9-shRNA
Cat No 
shAAV-222181
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human S100A9.

shAAV-222181
AAV-h-S100A9-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human S100A9 (S100 calcium binding protein A9). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
60B8AG; CAGB; calgranulin B; Calgranulin-B; calprotectin L1H subunit; CFAG; CGLB; L1AG; leukocyte L1 complex heavy chain; LIAG; MAC387; MIF; migration inhibitory factor-related protein 14; MRP14; MRP-14; NIF; P14; protein S100-A9; S100 calcium-binding protein A9
Description (eCommerce)
S100A9 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells and are involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100A9 is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. [taken from NCBI Entrez Gene (Gene ID: 6280)].
Description (Vector)
S100A9 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and altered expression of this protein is associated with the disease cystic fibrosis.
Gene ID
6280
Gene Name (eCommerce)
S100 calcium binding protein A9
Gene Name (Vector)
S100 calcium binding protein A9
Gene Symbol
S100A9
HGNC ID
HGNC:10499
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
345
Protein Name (eCommerce)
Protein S100-A9
RefSeq ID
NM_002965
RefSeq Synonyms
NM_002965, BC047681,
Research Areas
Apoptosis,Autophagy,Cytoskeleton,Immunology,Innate Immunity,Signal Transduction,Toll-like Receptor Signaling
Research Areas (Faceted)
cell_biology,immunology,signal_transduction
Species
human
Target Sentence
S100A9 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells and are involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100A9 is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. [taken from NCBI Entrez Gene (Gene ID: 6280)].
UniGene ID
Hs.112405
UniProt ID (eCommerce)
P06702

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.