human RXRB shRNA silencing AAV

Name
AAV-h-RXRB-shRNA

Cat No
shAAV-222147

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human RXRB.

shAAV-222147

AAV-h-RXRB-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human RXRB (retinoid X receptor beta). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

DAUDI6; H-2RIIBP; NR2B2; RCoR-1

Description (Vector)

RXRB encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the effects of retinoic acid (RA). The encoded protein forms homodimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. RXRB lies within the major histocompatibility complex (MHC) class II region on chromosome 6. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene ID

6257

Gene Name (Vector)

retinoid X receptor beta

Gene Symbol

RXRB

HGNC ID

HGNC:10478

ORF Size (aa)

1602

ORF Size (bp)

1602 bp

RefSeq ID

NM_021976

RefSeq Synonyms

NM_021976, NM_001291989, NM_001270401, BC001167,

Species

human

UniGene ID

Hs.388034

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.