human RTCD1 shRNA silencing AAV

Name 
AAV-h-RTCD1-shRNA
Cat No 
shAAV-222077
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human RTCA.

shAAV-222077
AAV-h-RTCD1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human RTCA (RNA 3′-terminal phosphate cyclase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
RPC; RTC1; RTCD1
Description (Vector)
RTCA encodes a member of the RNA 3'-phosphate cyclase family. The encoded protein plays a role in RNA metabolism by catalyzing the ATP-dependent conversion of the 3'-phosphate of RNA substrates to a 2',3'-cyclic phosphodiester. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene ID
8634
Gene Name (Vector)
RNA 3'-terminal phosphate cyclase
Gene Symbol
RTCA
HGNC ID
HGNC:17981
ORF Size (aa)
1140
ORF Size (bp)
1140 bp
RefSeq ID
NM_003729
RefSeq Synonyms
NM_003729, NM_001130841, BC012604,
Species
human
UniGene ID
Hs.484222

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.