human RPS10 shRNA silencing AAV

Name
AAV-h-RPS10-shRNA

Cat No
shAAV-221806

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human RPS10.

shAAV-221806

AAV-h-RPS10-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human RPS10 (ribosomal protein S10). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

DBA9; S10

Description (Vector)

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S10E family of ribosomal proteins. It is located in the cytoplasm. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternate splicing results in multiple transcript variants that encode the same protein. Naturally occurring read-through transcription occurs between this locus and the neighboring locus NUDT3 (nudix (nucleoside diphosphate linked moiety X)-type motif 3).

Gene ID

6204

Gene Name (Vector)

ribosomal protein S10

Gene Symbol

RPS10

HGNC ID

HGNC:10383

ORF Size (aa)

498

RefSeq ID

NM_001014

RefSeq Synonyms

NM_001204091, NM_001203245, NM_001014, BC073799, BC071946, BC070235, BC005012, BC001955, BC001032,

Species

human

UniGene ID

Hs.645317

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.