human RPLP0 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human RPLP0.
shAAV-221770
AAV-h-RPLP0-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human RPLP0 (ribosomal protein lateral stalk subunit P0). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
L10E; LP0; P0; PRLP0; RPP0
Description (Vector)
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein, which is the functional equivalent of the E. coli L10 ribosomal protein, belongs to the L10P family of ribosomal proteins. It is a neutral phosphoprotein with a C-terminal end that is nearly identical to the C-terminal ends of the acidic ribosomal phosphoproteins P1 and P2. The P0 protein can interact with P1 and P2 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer. The protein is located in the cytoplasm. Transcript variants derived from alternative splicing exist; they encode the same protein. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Gene ID
6175
Gene Name (Vector)
ribosomal protein lateral stalk subunit P0
Gene Symbol
RPLP0
HGNC ID
HGNC:10371
ORF Size (aa)
765
RefSeq ID
NM_001002
RefSeq Synonyms
NM_053275, NM_001002, BC107717, BC070194, BC015690, BC015173, BC009867, BC008594, BC008092, BC005863, BC003655, BC001834, BC001127, BC000752, BC000345, BC000087,
Species
human
UniGene ID
Hs.546285
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.