human RPH3A shRNA silencing AAV

Name
AAV-h-RPH3A-shRNA

Cat No
shAAV-221554

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human RPH3A.

shAAV-221554

AAV-h-RPH3A-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human RPH3A (rabphilin 3A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

Exocytosis of neurotransmitters and hormones is fundamental to synaptic neurotransmission and cell-cell communication. RAB3A (MIM 179390) is a small G protein that is thought to act at late stages of exocytosis, and RPH3A is a RAB3A effector (Lin et al., 2007 (PubMed 17149709)).(supplied by OMIM, Jul 2008)

Gene ID

22895

Gene Name (Vector)

rabphilin 3A

Gene Symbol

RPH3A

HGNC ID

HGNC:17056

ORF Size (aa)

2073

ORF Size (bp)

2073 bp

RefSeq ID

NM_014954

RefSeq Synonyms

NM_014954, NM_001143854, BC017259,

Species

human

UniGene ID

Hs.21239

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.