human RNF14 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human RNF14.
shAAV-221353
AAV-h-RNF14-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human RNF14 (ring finger protein 14). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ARA54; HFB30; HRIHFB2038; TRIAD2
Description (Vector)
RNF14 contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Six alternatively spliced transcript variants encoding two distinct isoforms have been reported.
Gene ID
9604
Gene Name (Vector)
ring finger protein 14
Gene Symbol
RNF14
HGNC ID
HGNC:10058
ORF Size (aa)
1425
ORF Size (bp)
1425 bp
RefSeq ID
NM_004290
RefSeq Synonyms
NM_183401, NM_183400, NM_183399, NM_183398, NM_004290, NM_001201365, BC144061, BC126185,
Species
human
UniGene ID
Hs.483616
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.