human RNF130 shRNA silencing AAV

Name 
AAV-h-RNF130-shRNA
Cat No 
shAAV-221348
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human RNF130.

shAAV-221348
AAV-h-RNF130-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human RNF130 (ring finger protein 130). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
G1RZFP; GOLIATH; GP
Description (Vector)
RNF130 contains a RING finger motif and is similar to g1, a Drosophila zinc-finger protein that is expressed in mesoderm and involved in embryonic development. The expression of the mouse counterpart was found to be upregulated in myeloblastic cells following IL3 deprivation, suggesting that this gene may regulate growth factor withdrawal-induced apoptosis of myeloid precursor cells.
Gene ID
55819
Gene Name (Vector)
ring finger protein 130
Gene Symbol
RNF130
HGNC ID
HGNC:18280
ORF Size (aa)
1260
ORF Size (bp)
1260 bp
RefSeq ID
NM_018434
RefSeq Synonyms
NM_018434, NM_001280801, BC113864, BC108306,
Species
human
UniGene ID
Hs.484363

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.