human RND3 shRNA silencing AAV

Cat. No: shAAV-221320

Availability: 6-8 weeks

Name: AAV-h-RND3-shRNA

This is an AAV expressing shRNA for silencing of Human RND3.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: RND3
Gene Name: Rho family GTPase 3
Gene ID: 390
Gene Synonyms: ARHE; memB; Rho8; RhoE
ORF Size: 735 bp
RefSeq#: NM_005168
Gene Description: RND3 encodes a protein which is a member of the small GTPase protein superfamily. The encoded protein binds only GTP but has no GTPase activity, and appears to act as a negative regulator of cytoskeletal organization leading to loss of adhesion. Multiple alternatively spliced variants, encoding the same protein, have been identified.
UniGene ID: Hs.713765
HGNC ID: HGNC:671