human RNASEL shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human RNASEL.
shAAV-221313
AAV-h-RNASEL-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human RNASEL (ribonuclease L). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
PRCA1; RNS4
Description (Vector)
RNASEL encodes a component of the interferon-regulated 2-5A system that functions in the antiviral and antiproliferative roles of interferons. Mutations in this gene have been associated with predisposition to prostate cancer and this gene is a candidate for the hereditary prostate cancer 1 (HPC1) allele.
Gene ID
6041
Gene Name (Vector)
ribonuclease L
Gene Symbol
RNASEL
HGNC ID
HGNC:10050
ORF Size (aa)
1959
ORF Size (bp)
1959 bp
RefSeq ID
NM_021133
RefSeq Synonyms
NM_021133, BC115697, BC114433, BC090934,
Species
human
UniGene ID
Hs.518545
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.