human RHOC shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human RHOC.
shAAV-221179
AAV-h-RHOC-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human RHOC (ras homolog family member C). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ARH9; ARHC; H9; RHOH9
Description (Vector)
RHOC encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Gene ID
389
Gene Name (Vector)
ras homolog family member C
Gene Symbol
RHOC
HGNC ID
HGNC:669
ORF Size (aa)
582
RefSeq ID
NM_175744
RefSeq Synonyms
NM_175744, NM_001042679, NM_001042678, BC052808, BC009177, BC007245,
Species
human
UniGene ID
Hs.658289
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.