human RGS3 shRNA silencing AAV

Name 
AAV-h-RGS3-shRNA
Cat No 
shAAV-221127
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human RGS3.

shAAV-221127
AAV-h-RGS3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human RGS3 (regulator of G-protein signaling 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
C2PA; RGP3
Description (Vector)
RGS3 encodes a member of the regulator of G-protein signaling (RGS) family. This protein is a GTP-ase activating protein which inhibits G-protein mediated signal transduction. The protein is largely cytosolic, but G-protein activation leads to translocation of this protein to the plasma membrane. A nuclear form of this protein has also been described, but its sequence has not been identified. Multiple alternatively spliced transcript variants have been described for this gene but the full-length nature of some transcripts is not yet known.
Gene ID
5998
Gene Name (Vector)
regulator of G-protein signaling 3
Gene Symbol
RGS3
HGNC ID
HGNC:9999
ORF Size (aa)
2754
ORF Size (bp)
2754 bp
RefSeq ID
NM_144489
RefSeq Synonyms
NM_144489, NM_144488, NM_134427, NM_130795, NM_021106, NM_017790, NM_001322215, NM_001322214, NM_001282923, NM_001282922, NM_001276262, NM_001276261, NM_001276260, BC042555, BC018072,
Species
human
UniGene ID
Hs.494875

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.