human RGS2 shRNA silencing AAV

Name
AAV-h-RGS2-shRNA

Cat No
shAAV-221121

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human RGS2.

shAAV-221121

AAV-h-RGS2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human RGS2 (regulator of G-protein signaling 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

G0S8

Description (Vector)

Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 2 belongs to this family. The protein acts as a mediator of myeloid differentiation and may play a role in leukemogenesis.

Gene ID

5997

Gene Name (Vector)

regulator of G-protein signaling 2

Gene Symbol

RGS2

HGNC ID

HGNC:9998

ORF Size (aa)

636

RefSeq ID

NM_002923

RefSeq Synonyms

NM_002923, BC007049,

Species

human

UniGene ID

Hs.78944

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.