human RBP4 shRNA silencing AAV

Name
AAV-h-RBP4-shRNA

Cat No
shAAV-220918

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human RBP4.

shAAV-220918

AAV-h-RBP4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human RBP4 (retinol binding protein 4). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

MCOPCB10; RDCCAS

Description (Vector)

This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells.

Gene ID

5950

Gene Name (Vector)

retinol binding protein 4

Gene Symbol

RBP4

HGNC ID

HGNC:9922

ORF Size (aa)

606

RefSeq ID

NM_006744

RefSeq Synonyms

NM_006744, NM_001323518, NM_001323517, BC020633,

Species

human

UniGene ID

Hs.50223

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.