human RBMX shRNA silencing AAV

Name
AAV-h-RBMX-shRNA

Cat No
shAAV-220899

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human RBMX.

shAAV-220899

AAV-h-RBMX-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human RBMX (RNA binding motif protein, X-linked). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

hnRNP-G; HNRNPG; HNRPG; MRXS11; RBMXP1; RBMXRT; RNMX

Description (Vector)

RBMX belongs to the RBMY gene family which includes candidate Y chromosome spermatogenesis genes. This gene, an active X chromosome homolog of the Y chromosome RBMY gene, is widely expressed whereas the RBMY gene evolved a male-specific function in spermatogenesis. Pseudogenes of this gene, found on chromosomes 1, 4, 9, 11, and 6, were likely derived by retrotransposition from the original gene. Alternatively spliced transcript variants encoding different isoforms have been identified. A snoRNA gene (SNORD61) is found in one of its introns.

Gene ID

27316

Gene Name (Vector)

RNA binding motif protein, X-linked

Gene Symbol

RBMX

HGNC ID

HGNC:9910

ORF Size (aa)

1176

ORF Size (bp)

1176 bp

RefSeq ID

NM_002139

RefSeq Synonyms

NM_002139, NM_001164803, BC007435, BC006550,

Species

human

UniGene ID

Hs.710162

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.