human RARA shRNA silencing AAV

Name 
AAV-h-RARA-shRNA
Cat No 
shAAV-220747
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human RARA.

shAAV-220747
AAV-h-RARA-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human RARA (retinoic acid receptor alpha). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
NR1B1; RAR
Description (Vector)
RARA represents a nuclear retinoic acid receptor. The encoded protein, retinoic acid receptor alpha, regulates transcription in a ligand-dependent manner. RARA has been implicated in regulation of development, differentiation, apoptosis, granulopoeisis, and transcription of clock genes. Translocations between this locus and several other loci have been associated with acute promyelocytic leukemia. Alternatively spliced transcript variants have been found for this locus.
Gene ID
5914
Gene Name (Vector)
retinoic acid receptor alpha
Gene Symbol
RARA
HGNC ID
HGNC:9864
ORF Size (aa)
1389
ORF Size (bp)
1389 bp
RefSeq ID
NM_000964
RefSeq Synonyms
NM_001145302, NM_001145301, NM_001024809, NM_000964, BC071733, BC008727,
Species
human
UniGene ID
Hs.654583

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.