human RANGRF shRNA silencing AAV

Name 
AAV-h-RANGRF-shRNA
Cat No 
shAAV-220712
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human RANGRF.

shAAV-220712
AAV-h-RANGRF-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human RANGRF (RAN guanine nucleotide release factor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HSPC165; HSPC236; MOG1; RANGNRF
Description (Vector)
RANGRF encodes a protein that has been shown to function as a guanine nucleotide release factor in mouse and to regulate the expression and function of the Nav1.5 cardiac sodium channel in human. Alternative splicing results in multiple transcript variants.
Gene ID
29098
Gene Name (Vector)
RAN guanine nucleotide release factor
Gene Symbol
RANGRF
HGNC ID
HGNC:17679
ORF Size (aa)
498
RefSeq ID
NM_016492
RefSeq Synonyms
NM_016492, NM_001330127, NM_001177802, NM_001177801, BC100017, BC012552, BC006486,
Species
human
UniGene ID
Hs.408233

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.