human RAB27A shRNA silencing AAV

Name
AAV-h-RAB27A-shRNA

Cat No
shAAV-220521

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human RAB27A.

shAAV-220521

AAV-h-RAB27A-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human RAB27A (RAB27A, member RAS oncogene family). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

GS2; HsT18676; RAB27; RAM

Description (Vector)

RAB27A belongs to the small GTPase superfamily, Rab family. The protein is membrane-bound and may be involved in protein transport and small GTPase mediated signal transduction. Mutations in this gene are associated with Griscelli syndrome type 2. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified.

Gene ID

5873

Gene Name (Vector)

RAB27A, member RAS oncogene family

Gene Symbol

RAB27A

HGNC ID

HGNC:9766

ORF Size (aa)

666

RefSeq ID

NM_004580

RefSeq Synonyms

NM_183236, NM_183235, NM_183234, NM_004580, BC136423, BC132800, BC107680,

Species

human

UniGene ID

Hs.654978

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.