human PTTG1IP shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PTTG1IP.
shAAV-220377
AAV-h-PTTG1IP-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PTTG1IP (pituitary tumor-transforming 1 interacting protein). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
C21orf1; C21orf3; PBF
Description (Vector)
The encoded protein, which directly binds to pituitary tumor-transforming gene 1 protein (PTTG1), facilitates the nuclear translocation of PTTG1 and potentiates the transcriptional activation of basic fibroblast growth factor by PTTG1. The gene product localizes to both the cytoplasm and nucleus. Its NLS is required for its own nuclear localization, the nuclear localization of PTTG1, and its interaction with PTTG1.
Gene ID
754
Gene Name (Vector)
pituitary tumor-transforming 1 interacting protein
Gene Symbol
PTTG1IP
HGNC ID
HGNC:13524
ORF Size (aa)
543
RefSeq ID
NM_004339
RefSeq Synonyms
NM_004339, NM_001286822, BC034250, BC031097, BC020983, BC019295, BC012858, BC000415,
Species
human
UniGene ID
Hs.474010
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.